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Middleton Lab

University of Missouri - Integrative Anatomy

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Publications

Here’s a link to my Google Scholar Profile.

  1. Gatesy, SM and KM Middleton. 1997. Bipedalism, flight, and the evolution of theropod locomotor diversity. Journal of Vertebrate Paleontology 17(2): 308-329. Data: http://dx.doi.org/10.5061/dryad.jf6ht
  2. Gatesy, SM and KM Middleton. 1999. Theropod hind limb disparity revisited: a response. Journal of Vertebrate Paleontology 19(3): 606.
  3. Gatesy, SM, KM Middleton, FA Jenkins, Jr, and NH Shubin. 1999. Three dimensional preservation of foot movements in Triassic theropod dinosaurs. Nature 399: 141-144.
  4. Middleton, KM and SM Gatesy. 2000. Theropod forelimb design and evolution. Zoological Journal of the Linnean Society 28(2): 149-187. Data: http://dx.doi.org/10.5061/dryad.jf6ht
  5. Middleton, KM 2001. The morphological basis of hallucal orientation in extant birds. Journal of Morphology 250: 51-60.
  6. Tian, X., J Iriarte-Díaz, KM Middleton, R Galvao, E Israeli, A Roemer, A Sullivan, A Song, SM Swartz and KB Breuer. 2006. Direct measurements of the kinematics and dynamics of bat flight. Bioinspiration & Biomimetics 1: S10-S18.
  7. Swartz, SM and KM Middleton. 2008. Biomechanics of the bat limb skeleton: Scaling, material properties, and mechanics. 2008. Cells, Tissues and Organs 187(1): 59-84.
  8. Middleton, KM, CE Shubin, DC Moore, T Garland, Jr, PA Carter, and SM Swartz. 2008. The relative importance of genetics and phenotypic plasticity in dictating bone morphology and mechanics in aged mice: Evidence from an artificial selection experiment. Zoology 111(2): 135-147.
  9. Lavin, SR, WH Karasov, AR Ives, KM Middleton, and T Garland, Jr. 2008. Morphometrics of the avian small intestine, compared with nonflying mammals. Physiological and Biochemical Zoology 81(5): 526-550.
  10. Hannon, RM, SA Kelly, KM Middleton, EM Kolb, D Pomp, and T Garland, Jr. 2008. Phenotypic Effects of the “Mini-Muscle” Allele in a Large HR x C57BL/6J Mouse Backcross. Journal of Heredity 99(4): 349-354.
  11. Clarke, JA and KM Middleton. 2008. Mosaicism, modules, and the evolution of birds: Results from a Bayesian approach to the study of morphological evolution using discrete character data. Systematic Biology 57(2): 185-201.
  12. Middleton, KM, SA Kelly, and T Garland, Jr. 2008. Selective breeding and skeletal response to high voluntary activity in mice. Integrative and Comparative Biology 48(3): 394-410.
  13. Keeney, BK, DA Raichlen, TH Meek, RS Wijeratne, KM Middleton, GL Gerdeman, and T Garland, Jr. 2008. Differential response to a selective cannabinoid receptor antagonist (SR141716: Rimonabant) in female mice from lines selectively bred for high voluntary wheel-running behavior. Behavioural Pharmacology 19: 812-820.
  14. Malisch, JL, CW Breuner, EM Kolb, H Wada, RM Hannon, MA Chappell, KM Middleton, and T Garland, Jr. 2009. Behavioral despair and home-cage activity in mice with chronically elevated baseline corticosterone concentrations. Behavior Genetics 39: 192-201.
  15. Eisenmann, JC, EE Wickel, SA Kelly, KM Middleton, and T Garland, Jr. 2009. Day-to-day variability in voluntary wheel running among young mice selectively bred for high activity. European Journal of Applied Physiology 106: 613-619.
  16. Middleton, KM, BD Goldstein, PR Guduru, JF Waters, SA Kelly, SM Swartz, and T Garland, Jr. 2010. Variation in within-bone stiffness measured by nanoindentation in mice bred for high levels of voluntary wheel running. Journal of Anatomy 216: 121-131.
  17. Kolb, EM, SA Kelly, KM Middleton, LS Sermsakdi, MA Chappell, and T Garland, Jr. 2010. Erythropoietin elevates VO2max but not voluntary wheel running in mice. Journal of Experimental Biology 213: 510-519.
  18. Wallace, IJ, KM Middleton, S Lublinsky, SA Kelly, S Judex, T Garland, Jr., B Demes. 2010. Functional significance of genetic variation underlying limb bone diaphyseal structure. American Journal of Physical Anthropology 143: 21-30.
  19. Riskin, DK, J Iriarte-Díaz, KM Middleton, KS Breuer, SM Swartz. 2010. The effect of body size on the wing movements of pteropodid bats, with insights into thrust and lift production. Journal of Experimental Biology 213: 4110-4122.
  20. Garland, T Jr, SA Kelly, JL Malisch, EM Kolb, RM Hannon, BK Keeney, SL Van Cleave, KM Middleton. 2011. How to run far: multiple solutions and sex-specific responses to selective breeding for high voluntary activity levels. Proceedings of the Royal Society B 278:574-581.
  21. Keeney, BK, TH Meek, KM Middleton, and T Garland, Jr. 2012. Sex differences in cannabinoid receptor-1 (CB1) pharmacology in mice selectively bred for high voluntary wheel-running behavior. Pharmacology, Biochemistry and Behavior 101: 528-537.
  22. Altshuler, DL, EM Quicazán-Rubio, PS Segre, KM Middleton. 2012. Wingbeat kinematics and motor control of yaw turns in Anna’s hummingbird (Calypte anna). Journal of Experimental Biology 215: 4070-4084.
  23. Cheney, JA, N Konow, KM Middleton, KS Breuer, TJ Roberts, EL Giblin, and SM Swartz. 2014. Membrane muscle function in the compliant wings of bats. Bioinspiration and Biomimetics 9: 025007. Press coverage: Brown University, Science Daily, New York Times Sciencetake
  24. Read TJG, PS Segre, KM Middleton, DL Altshuler. 2016. Hummingbirds control turning velocity using body orientation and turning radius using asymmetrical wingbeat kinematics. Journal of the Royal Society, Interface 13: 20160110.

Invited Reviews

  1. Clarke, JA and KM Middleton. 2006. Bird evolution. Current Biology 16: R350-R354.
  2. Middleton, KM and LT English. 2014. Challenges and advances in the study of pterosaur flight. Canadian Journal of Zoology: Advanced online publication.

Book Chapters

  1. Gatesy, SM and KM Middleton}. 2007. Skeletal adaptations for flight. pp. 269-283 in Fins into Limbs: Evolution, Development, and Transformation. BK Hall, ed. University of Chicago Press.
  2. Owerkowicz, T, C Musinsky, KM Middleton, AW Crompton. in press. Respiratory turbinates in extant mammals and birds: the Rosetta bone in the evolution of endothermy? in Shubin, NH, KP Dial, EL Brainerd, eds. Great Transformations in Vertebrate Evolution. University of Chicago Press.

Book Reviews

  1. Middleton, KM. 2003. Dinosaurs of the Air: The Evolution and Loss of Flight in Dinosaurs and Birds and Mesozoic Birds: Above the Heads of Dinosaurs. Palaeontologia Electronica 6: 5.

Recent Abstracts

  1. Tsai, HP, KM Middleton, CM Holliday. 2015. More than one way to be a giant: convergence and disparity in saurischian dinosaur hip joints during body size evolution. Integrative and Comparative Biology 55: e186.
  2. Cheney, JA, N Konow, KM Middleton, KS Breuer, TJ Roberts, EL Giblin, SM Swartz. 2015. Shaping the wings of bats: Muscle and wing skin interactions in flight. Integrative and Comparative Biology 55: e29.
  3. Smolinsky, AN, KM Middleton, F Pfeiffer, CM Holliday. 2015. Material properties of the mandibular symphysis in Alligator mississippiensis. Integrative and Comparative Biology 55: e173.
  4. Tsai, HP, KM Middleton, CM Holliday. 2015. Solutions for gigantism: evolutionary and biomechanical implications of dinosaur hip joint soft tissues. FASEB J 29(1, suppl.): 351.4.
  5. Cost, IN, A Spates, KC Sellers, JL Davis, KM Middleton, LM Witmer, CM Holliday. 2015. Biomechanics of the avian feeding apparatus. Society of Vertebrate Paleontology 2015 Annual Meeting, Dallas, TX. Journal of Vertebrate Paleontology, Program and Abstracts, 2015: 110.
  6. KC Sellers, JL Davis, KM Middleton, CM Holliday. 2015. Ontogeny and biomechanics of the American alligator skull. Society of Vertebrate Paleontology 2015 Annual Meeting, Dallas, TX. Journal of Vertebrate Paleontology, Program and Abstracts, 2015: 211.
  7. Kuo S and KM Middleton. 2016. Tensile mechanical properties of isolated penguin flipper feathers. Society for Integrative and Comparative Biology 2016 Annual Meeting, Portland, OR.
  8. Middleton KM, SJ Peacock, BR Coats, JK Kirkland, T Garland, Jr. 2016. Comparison of morphology and bending mechanics of femora in response to chronic exercise in three strains of mice. American Association of Anatomists 2016 Annual Meeting, San Diego, CA.